The article titled "Obstructive sleep apnea - diagnosis, medical management and dental implications" by K.R.Magliocca and J.I.Melman
was published in the Journal of the American Dental Association (JADA)
in Aug 2005 [Vol 136(8): pages1121-9]. However, I found a miniaturised and
plagiarised version of this paper published in the Hong Kong Medical Diary (Vol.15, Issue No.3, March 2010)
by Prof. Lim Cheung and Dr. Hannah Chua. This article is available online at www.fmshk.org/database/articles/03db1.pdf
Please find a side by side comparisons of the similarities between the 2 articles at the end. Incidentally this is the same article in which Dr. Chua tried to pretend as an Assistant Professor (the related newspaper reports can be accessed at
http://www.hotjetso.com/thread-11311-1-1.html
http://www1.hk.apple.nextmedia.com/template/apple/art_main.php?iss_id=20101004&sec_id=4104&subsec_id=11867&art_id=14516496)
The journal has corrected Dr. Chua's academic designation after these news reports. However, it would not be possible to correct the plagiarism in this article as its quite widespread.
Article by Chua
and Cheung
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JADA article by
Magliocca and Melman
|
Obstructive
sleep apnoea (OSA) is a disturbance in normal sleep patterns.
|
Obstructive
sleep apnea (OSA) is a disturbance in normal sleep patterns
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The common morbidities of OSA are hypertension,1 depression,2
stroke,3 angina,4 cardiac dysrhythmia,5……..
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……comorbid disease in connection with untreated
OSA such as systemic hypertension,1–3
depression,4 stroke,5,6 angina7 and
cardiac dysrhythmias.8
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Untreated
OSA is also associated with motor vehicle accidents,6 poor work
performance, occupational accidents and reduced quality of life.4
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Untreated
OSA also is associated with motor vehicle accidents,9 poor work
performance, occupational accidents and reduced quality of life.10,11
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Epidemiology
OSA occurs
in 2 to 4 percent of the adult population between the ages of 30 to 60 years,
though evidence suggests that many more patients remain undiagnosed.
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EPIDEMIOLOGY
OSA occurs
in 2 to 4 percent of the adult population between the ages of 30 to 60 years,16
though evidence suggests that many more patients remain undiagnosed.
|
Signs and
Symptoms
The common signs and symptoms associated with OSA are:
loud, habitual snoring, apnoeic events witnessed by the spouse or others,
daytime sleepiness,
restless sleep, choking sensation or gasping during the
night, morning headache,
personality and mood changes, sexual dysfunction (impotence and decreased libido) and gastro-oesophageal reflux.
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SIGNS AND SYMPTOMS
Some of the
signs and symptoms listed in Box. 1 have been copied including
Excessive sleepiness
Sleep
restlessness
Choking or
gasping
Morning
headaches
Decreased
libido
Impotence
Gastroesophageal
reflux disease
|
The most common
orofacial characteristic encountered include retrognathic mandible, narrow
palate, long soft
palate, hypertrophic
tonsils, nasal septal deviation and relative macroglossia.
|
The most
common orofacial characteristics encountered include a retrognathic mandible,
narrow palate, large neck circumference, long soft palate (which leads to dentists’ being unable to
visualize the entire length of the uvula when the patient’s mouth is open
wide), tonsillar
hypertrophy, nasal septal deviation and relative macroglossia.
|
The gold
standard for diagnosing OSA is by polysomnography (PSG), which needs to be conducted at a sleep
laboratory.
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The gold
standard for diagnosing OSA involves having the patient complete
polysomnography (an overnight sleep study) conducted in a laboratory.
|
The aims of polysomnography are to evaluate any
abnormal sleep breathing, sleep architecture and oxygen saturation. A typical hours
nocturnal laboratory PSG involves measurements of multiple physiological
functions including electro-oculography,
chin or leg movement via electromyography, electrocardiography, sleep
positioning, respiratory activity and oxygen saturation.
|
The polysomnogram records parameters including
(brain waves), electro-oculography
(eye movement), electrocardiography,
electromyography (chin and leg movement), sleep positioning, respiratory
activity and oxygen saturations.
|
the apnoea-hypopnoea index (AHI) which is the number of apnoeas and hypopnoeas
per hour of sleep.
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The apnea-hypopnea index (AHI) is the average number of apneas and
hypopneas per hour of sleep.
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Apnoea is
defined as the cessation of air flow (complete obstruction) for at least 10
seconds with a concomitant 2 to 4 percent drop in arterial oxygen saturation. Hypopnoea is
defined as a reduction
in airflow of at least 30 to 50 percent with a drop in oxygen saturation.
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Apnea is
defined as the cessation of airflow—a complete obstruction for at least 10
seconds—with a concomitant 2 to 4 percent drop in arterial oxygen saturation.26 The definition
of hypopnea is more variable, but it commonly is thought of as a reduction in airflow of
at least 30 to 50 percent with a drop in oxygen saturation.
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The severity of OSA is commonly classified according
to a patient's AHI score: mild
(AHI score between 5 to 15); Moderate (AHI score between 15 and 30); and
severe (AHI score greater than 30). Other factors that also influence the severity of OSA
include oxygen desaturation, quality of life and the level of daytime
sleepiness
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OSA severity is classified on the basis of the
patient’s AHI score, into three categories: mild (AHI score between 5 and 15), moderate (AHI score
between 15 and 30) and severe (AHI score greater than 30). Not all
studies, however, adhere to the numerical parameters of this classification. Other factors that also
influence the severity of OSA include oxygen desaturation, quality of life
and the level of daytime sleepiness
|
Possible
treatment options for adult patients diagnosed with OSA are based on the
severity of the sleep disorder, patient's preference and his/her overall health
status. Positional
therapy involves nocturnal aids to prevent patients from sleeping in a supine
position. Sleeping in the lateral position is generally recommended, as it will displace the tongue
from the posterior airway such that it is less likely to cause airway
obstruction during sleep.
|
possible
treatment options for adult patients with OSA based on the severity of the
sleep disorder, patient’s preference, the patient’s overall health, and the
experience and preferences of the team members. Positional therapy involves nocturnal aids (for
example, having patients sew a tennis ball into the back of their pajama
tops) to prevent
patients from sleeping in a supine position. Sleeping in the lateral position
may be effective, as
it will displace the tongue from the posterior airway such that it is less
likely to be a source of obstruction.
|
Weight loss
is
universally recommended
for obese patients. However, it is not known how much weight loss is required to eliminate OSA,
and both the patient's gender
and weight distribution may contribute to his or her OSA in an unpredictable
manner
|
Weight loss
is recommended when applicable; however, not all patients with OSA are obese.29,30
It is not known how much
weight loss is required to eliminate OSA, and both the patient’s sex and weight
distribution may contribute to his or her OSA in an unpredictable manner
|
The concept
of nasal CPAP is to maintain upper airway patency during sleep. This
treatment can be administered via either a nasal or oral mask. Due to its effectiveness, CPAP is first-line
treatment and the primary form of therapy for OSA, although its success is
limited by the patient's level of compliance. About 20 to 30 percent of patients experience
problems using CPAP, and the device is ineffective if it is not regularly
used. The common problems associated with CPAP are nasal dryness, facial
ulceration at the mask interface and claustrophobia.
|
The concept
of nasal CPAP is to maintain upper airway patency during sleep by way of a
pneumatic stent. This treatment can be administered via nasal mask, oral mask or other
variations. Because of its
effectiveness, CPAP is the first-line treatment and the primary form of
therapy for OSA, though its success is limited by the patient’s level of
compliance. Roughly 20
to 30 percent of patients experience problems while using CPAP, and the
device is ineffective if it is not used regularly.35
Patients list nasal
dryness, facial ulcerations at the mask interface and claustrophobia
|
Many
commercial devices offer treatment for snoring; however a device designed to treat
OSA should be fabricated by a dental practitioner or specialist familiar with
device design, maintenance and therapeutic efficacy. A multitude of oral appliances for OSA are
available, but not all patients find the same appliance effective. Patient's compliance with oral
appliances appears to be adequate but not all studies agree. Difficulty with the device,
owing to temporary or persistent occlusal disturbance, temporomandibular joint
or individual tooth discomfort or perceived lack of ûcacy may cause
compliance issues.
|
Many
commercial devices offer treatment for snoring; however, a device designed to
treat OSA should be fabricated by a dentist familiar with device design,
maintenance and therapeutic efficacy and who has an association with and
referral from a sleep team. A multitude of oral appliances for OSA are available, but not all
patients will find the same appliance effective.13 Patient compliance with oral
appliances appears to be adequate,37 but not all studies agree.38
Difficulty with the
device owing to temporary or persistent occlusal, temporomandibular joint or
individual tooth discomfort13 or a perceived lack of efficacy may
cause compliance issues.
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The main
surgical treatments offered for OSA often target the anatomical areas of the
posterior airway where collapse is suspected to occur. Treatment is designed
to enlarge the posterior airway space, reduce airway collapsibility and
stabilise the airway in the long term.
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The main
surgical treatments offered for OSA often target the anatomical areas of the
posterior airway where collapse is suspected to occur. Treatment is designed
to enlarge the posterior airway space, reduce airway collapsibility and,
ideally, stabilize the airway for the long term.
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Orthognathic surgery has the advantage of correcting any
craniofacial abnormalities that may have caused the OSA.
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Surgery has the advantage of correcting any craniofacial abnormalities that
may have caused the OSA……
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Maxillomandibular
advancement surgery (MMA), which is based on conventional orthognathic surgery
techniques has been proven ûective in retrospective studies for a range of
OSA
patients
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Maxillomandibular
advancement (MMA) surgery, which is based on traditional orthognathic surgery
techniques, has been proven effective in retrospective studies for a range of
OSA
disease.
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